There are several avenues to
pursue that may decrease any one person's risk of developing breast cancer.
These include specific aspects of your lifestyle,
regular recommended screening depending upon
your risk, and in some cases of individuals at high risk medical or surgical treatments.
and Physicians at UC Irvine are working to provide better tools for
understanding and assessing an individual's risk, to decrease that risk and
prevent them from developing breast cancer, and to improve screening through research.
Levin is studying a recently described new type of estrogen receptor
that appears to play a larger role in breast cancer than normal breast tissue.
Thus, this type of estrogen receptor is a potential target for ways to modify
the effects of estrogens on the development of breast cancer. Dr. Bruce Blumberg is conducting studies for a new
receptor for steroids, which also responds to drugs and other things in our
environment, that is over-expressed in breast cancer and that modifies the
immune system. He is working to identify how this receptor works, how
environmental exposures might influence breast tumor development through this
receptor, and how we might target it to either decrease the risk of developing
cancer or change the biology of a tumor so we can treat it better.